Varaico: Literature-Extracted Genetic Variants

Gene:TRAF7
Variant:p.K615E
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TRAF7

NM_032271.3:p.K615E

Associated Papers

A comprehensive benchmark for multiple highly efficient base editors with broad targeting scope.

Wang X et al.

Biorxiv : the Preprint Server for Biology, 2025

39763781 (PubMed )
Supplement: media-3.xlsx › ABE_screen_library

Normal meninges harbor oncogenic somatic mutations in meningioma-driver genes.

Boetto J et al.

Acta Neuropathologica, 2023

Super-enhancer hijacking drives ectopic expression of hedgehog pathway ligands in meningiomas.

Youngblood MW et al.

Nature Communications, 2023

37805627 (PubMed )
Supplement: 41467_2023_41926_MOESM3_ESM.xlsx › SD1

Uncovering the molecular landscape of meningiomas and the impact of perioperative steroids on patient survival.

Furtak J et al.

Acta Neurochirurgica, 2023

Pleiotropic role of TRAF7 in skull-base meningiomas and congenital heart disease.

Mishra-Gorur K et al.

Proceedings of the National Academy of Sciences of the United States of America, 2023

Prognostic impact of genetic alterations and methylation classes in meningioma.

Berghoff AS et al.

Brain Pathology (zurich, Switzerland), 2022

35213082 (PubMed )
Supplement: BPA-32-e12970-s001.xlsx › Sheet1

Clinicopathologic Characteristics of Grade 2/3 Meningiomas: A Perspective on the Role of Next-Generation Sequencing.

Kim J et al.

Frontiers in Oncology, 2022

35774130 (PubMed )
Supplement: DataSheet_2.xlsx › Sheet2

Whole-Exome Sequencing Reveals Recurrent but Heterogeneous Mutational Profiles in Sporadic WHO Grade 1 Meningiomas.

González-Tablas M et al.

Frontiers in Oncology, 2021

34868937 (PubMed )
Supplement: DataSheet_1.docx

Phenotypic spectrum and transcriptomic profile associated with germline variants in TRAF7.

Castilla-Vallmanya L et al.

Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2020

Molecular characterization of localized pleural mesothelioma.

Hung YP et al.

Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, 2020

Whole exome sequencing of multiple meningiomas with varying histopathological presentation in one patient revealed distinctive somatic mutation burden and independent clonal origins.

Sheng HS et al.

Cancer Management and Research, 2019

Genetic landscape of meningioma.

Yuzawa S et al.

Brain Tumor Pathology, 2016

Genomic analysis of non-NF2 meningiomas reveals mutations in TRAF7, KLF4, AKT1, and SMO.

Clark VE et al.

Science (new York, N.y.), 2013

Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations.

Reuss DE et al.

Acta Neuropathologica, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."