Varaico: Literature-Extracted Genetic Variants

Gene:TREH
Variant:p.P301L
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TREH

NM_007180.3:p.P301L

Associated Papers

Prominent tauopathy and intracellular β-amyloid accumulation triggered by genetic deletion of cathepsin D: implications for Alzheimer disease pathogenesis.

Terron HM et al.

Alzheimer's Research & Therapy, 2024

A novel tauopathy model mimicking molecular and spatial aspects of human tau pathology.

Yanai R et al.

Brain Communications, 2024

Prominent tauopathy and intracellular β-amyloid accumulation triggered by genetic deletion of cathepsin D: Implications for Alzheimer disease pathogenesis.

Terron HM et al.

Research Square, 2023

Axonal Degeneration in Tauopathies: Disease Relevance and Underlying Mechanisms.

Kneynsberg A et al.

Frontiers in Neuroscience, 2017

Co-expression of truncated and full-length tau induces severe neurotoxicity.

Ozcelik S et al.

Molecular Psychiatry, 2016

Riluzole rescues alterations in rapid glutamate transients in the hippocampus of rTg4510 mice.

Hunsberger HC et al.

Metabolic Brain Disease, 2016

Hyperactivity with Agitative-Like Behavior in a Mouse Tauopathy Model.

Jul P et al.

Journal of Alzheimer's Disease : Jad, 2016

P301L tau expression affects glutamate release and clearance in the hippocampal trisynaptic pathway.

Hunsberger HC et al.

Journal of Neurochemistry, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."