Varaico: Literature-Extracted Genetic Variants

Gene:TREM2
Variant:p.T85K
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TREM2

NM_018965.4:p.T85K

Associated Papers

Dynamic insights into the effects of nonsynonymous polymorphisms (nsSNPs) on loss of TREM2 function.

Dash R et al.

Scientific Reports, 2022

35672339 (PubMed )
Supplement: 41598_2022_13120_MOESM6_ESM.doc

Mechanistic insights into the deleterious roles of Nasu-Hakola disease associated TREM2 variants.

Dash R et al.

Scientific Reports, 2020

32107424 (PubMed )
Supplement: 41598_2020_60561_MOESM1_ESM.docx

Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, but the Alzheimer's R47H mutant increases Aβ aggregation.

Vilalta A et al.

The Journal of Biological Chemistry, 0

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