Varaico: Literature-Extracted Genetic Variants

Gene:TREM2
Variant:p.K48M
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TREM2

NM_018965.4:p.K48M

Associated Papers

Multimerization of TREM2 is impaired by Alzheimer's disease-associated variants.

Dean HB et al.

Alzheimer's & Dementia : the Journal of the Alzheimer's Association, 2024

TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia.

Yeh FL et al.

Neuron, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."