Varaico: Literature-Extracted Genetic Variants

Gene:TRIM21
Variant:p.D355A
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TRIM21

NM_003141.4:p.D355A

Associated Papers

Defining the Antitumor Mechanism of Action of a Clinical-stage Compound as a Selective Degrader of the Nuclear Pore Complex.

Yuan L et al.

Cancer Discovery, 2025

State-selective small molecule degraders that preferentially remove aggregates and oligomers.

Luptak J et al.

Nature Communications, 2025

Selective degradation of multimeric proteins by TRIM21-based molecular glue and PROTAC degraders.

Lu P et al.

Cell, 2024

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."