Varaico: Literature-Extracted Genetic Variants

Gene:TRIM28
Variant:p.P22Q
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TRIM28

NM_005762.3:p.P22Q

Associated Papers

TRIM28 facilitates type I interferon activation by targeting TBK1.

Hua F et al.

Frontiers in Immunology, 2024

TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy.

Song T et al.

The Journal of Biological Chemistry, 2023

HIF-1 Interacts with TRIM28 and DNA-PK to release paused RNA polymerase II and activate target gene transcription in response to hypoxia.

Yang Y et al.

Nature Communications, 2022

TRIM17 and TRIM28 antagonistically regulate the ubiquitination and anti-apoptotic activity of BCL2A1.

Lionnard L et al.

Cell Death and Differentiation, 2019

Depleting Trim28 in adult mice is well tolerated and reduces levels of α-synuclein and tau.

Rousseaux MW et al.

Elife, 2018

TRIM28 regulates the nuclear accumulation and toxicity of both alpha-synuclein and tau.

Rousseaux MW et al.

Elife, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."