Varaico: Literature-Extracted Genetic Variants

Gene:TRIM37
Variant:p.C18R
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TRIM37

NM_015294.6:p.C18R

Associated Papers

Dynamic regulation of K33- and K48-linked ubiquitination of Tip60 by TRIM37 orchestrates host DNA damage response during Pseudomonas aeruginosa infection and recovery.

Yu H et al.

Microbiological Research, 2026

TRIM37 recognizes a bipartite degron to ubiquitinate centrosome substrates.

Stachera WE et al.

Biorxiv : the Preprint Server for Biology, 2025

TRIM37 prevents ectopic spindle pole assembly by peptide motif recognition and substrate-dependent oligomerization.

Bellaart A et al.

Nature Structural & Molecular Biology, 2025

TRIM37 employs peptide motif recognition and substrate-dependent oligomerization to prevent ectopic spindle pole assembly.

Bellaart A et al.

Biorxiv : the Preprint Server for Biology, 2024

Mesoscale regulation of MTOCs by the E3 ligase TRIM37.

Yeow ZY et al.

Biorxiv : the Preprint Server for Biology, 2024

The TRIM37 variants in Mulibrey nanism patients paralyze follicular helper T cell differentiation.

Gu W et al.

Cell Discovery, 2023

TRIM37 Augments AP-2γ Transcriptional Activity and Cellular Localization via K63-linked Ubiquitination to Drive Breast Cancer Progression.

Cui G et al.

International Journal of Biological Sciences, 2022

TRIM37 prevents formation of condensate-organized ectopic spindle poles to ensure mitotic fidelity.

Meitinger F et al.

The Journal of Cell Biology, 2021

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

Yeow ZY et al.

Nature, 2020

TRIM37, a novel E3 ligase for PEX5-mediated peroxisomal matrix protein import.

Wang W et al.

The Journal of Cell Biology, 2017

TRIM37 is a new histone H2A ubiquitin ligase and breast cancer oncoprotein.

Bhatnagar S et al.

Nature, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."