Associated Papers
Autosomal recessive hypertrophic cardiomyopathy associated with variants in TRIM63.
Bonanni F et al.
International Journal of Cardiology, 2026
Coiled-coil-domain-mediated TRIM E3 protein condensation modulates enzymatic activity and functional specificity.
Chen Q et al.
Cell Reports, 2025
HCM-Associated MuRF1 Variants Compromise Ubiquitylation and Are Predicted to Alter Protein Structure.
Chunthorng-Orn J et al.
International Journal of Molecular Sciences, 2025
TRIM22 functions as a scaffold protein for autophagy initiation.
Park H et al.
Animal Cells and Systems, 2025
Case Report: Two New Cases of Autosomal-Recessive Hypertrophic Cardiomyopathy Associated With TRIM63-Compound Heterozygous Variant.
Andreeva S et al.
Frontiers in Genetics, 2022
Clinical significance of genetic variation in hypertrophic cardiomyopathy: comparison of computational tools to prioritize missense variants.
Barbosa P et al.
Frontiers in Cardiovascular Medicine, 2022
36061567 (PubMed )
Supplement: Table_1.XLSX › Table_S1
Genetic evaluation of cardiomyopathies in Qatar identifies enrichment of pathogenic sarcomere gene variants and possible founder disease mutations in the Arabs.
Al-Shafai KN et al.
Molecular Genetics & Genomic Medicine, 2021
34137518 (PubMed )
Supplement: MGG3-9-e1709-s001.xlsx › Sheet1
Systems Analysis Implicates WAVE2 Complex in the Pathogenesis of Developmental Left-Sided Obstructive Heart Defects.
Edwards JJ et al.
Jacc. Basic to Translational Science, 2020
32368696 (PubMed )
Supplement: mmc3.xlsx › Cases
Evaluating the Clinical Validity of Hypertrophic Cardiomyopathy Genes.
Ingles J et al.
Circulation. Genomic and Precision Medicine, 2019
30681346 (PubMed )
Supplement: hcg-12-e002460-s001.pdf
Prioritizing causal disease genes using unbiased genomic features.
Deo RC et al.
Genome Biology, 2014
25633252 (PubMed )
Supplement: 13059_2014_534_MOESM48_ESM.xlsx › Sheet1
The role of ubiquitin ligases in cardiac disease.
Willis MS et al.
Journal of Molecular and Cellular Cardiology, 2014
Integrated analysis of germline and somatic variants in ovarian cancer.
Kanchi KL et al.
Nature Communications, 2014
24448499 (PubMed )
Supplement: NIHMS551112-supplement-7.xlsx › S_Data_6
Global DNA methylation and transcriptional analyses of human ESC-derived cardiomyocytes.
Gu Y et al.
Protein & Cell, 2013
Human molecular genetic and functional studies identify TRIM63, encoding Muscle RING Finger Protein 1, as a novel gene for human hypertrophic cardiomyopathy.
Chen SN et al.
Circulation Research, 2012
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