Varaico: Literature-Extracted Genetic Variants

Gene:TRIM72
Variant:p.C144S
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TRIM72

NM_001008274.4:p.C144S

Associated Papers

MG53: A new protagonist in the precise treatment of cardiomyopathies.

Zhao Q et al.

Biochemical Pharmacology, 2024

Structure and activation of the RING E3 ubiquitin ligase TRIM72 on the membrane.

Park SH et al.

Nature Structural & Molecular Biology, 2023

37770719 (PubMed )
Supplement: 41594_2023_1111_MOESM3_ESM.pdf

Structural basis for TRIM72 oligomerization during membrane damage repair.

Ma Y et al.

Nature Communications, 2023

Blocking MG53S255 Phosphorylation Protects Diabetic Heart From Ischemic Injury.

Lv F et al.

Circulation Research, 2022

The Pivotal Role of Mitsugumin 53 in Cardiovascular Diseases.

Jiang W et al.

Cardiovascular Toxicology, 2021

A knock-in mutation at cysteine 144 of TRIM72 is cardioprotective and reduces myocardial TRIM72 release.

Fillmore N et al.

Journal of Molecular and Cellular Cardiology, 2019

S-nitrosylation of TRIM72 at cysteine 144 is critical for protection against oxidation-induced protein degradation and cell death.

Kohr MJ et al.

Journal of Molecular and Cellular Cardiology, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."