Varaico: Literature-Extracted Genetic Variants

Gene:TRPA1
Variant:p.C621S
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TRPA1

NM_007332.3:p.C621S

Associated Papers

Molecular mechanism of hyperactivation conferred by a truncation of TRPA1.

Bali A et al.

Nature Communications, 2023

37208332 (PubMed )
Supplement: 41467_2023_38542_MOESM4_ESM.xlsx › Plasmid_and_Primers_List

Potent Activation of Human but Not Mouse TRPA1 by JT010.

Matsubara M et al.

International Journal of Molecular Sciences, 2022

Structural Pharmacology of TRP Channels.

Zhao Y et al.

Journal of Molecular Biology, 2021

Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel.

Suo Y et al.

Neuron, 2020

An environmental pollutant, 9,10-phenanthrenequinone, activates human TRPA1 via critical cysteines 621 and 665.

Muraki K et al.

Pharmacology Research & Perspectives, 2017

LE135, a retinoid acid receptor antagonist, produces pain through direct activation of TRP channels.

Yin S et al.

British Journal of Pharmacology, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."