Varaico: Literature-Extracted Genetic Variants

Gene:TRPA1
Variant:p.G12V
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TRPA1

NM_007332.3:p.G12V

Associated Papers

Genetics of brain arteriovenous malformations and cerebral cavernous malformations.

Hongo H et al.

Journal of Human Genetics, 2023

KRAS: From undruggable to a druggable Cancer Target.

Uprety D et al.

Cancer Treatment Reviews, 2020

Genomic heterogeneity of multiple synchronous lung cancer.

Liu Y et al.

Nature Communications, 2016

27767028 (PubMed )
Supplement: ncomms13200-s1.pdf

Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders.

Gremer L et al.

Human Mutation, 2011

PARG1, a protein-tyrosine phosphatase-associated RhoGAP, as a putative Rap2 effector.

Myagmar BE et al.

Biochemical and Biophysical Research Communications, 2005

Oncogenic insertional mutations in the P-loop of Ras are overactive in MAP kinase signaling.

Klockow B et al.

Oncogene, 2000

Identification of neurofibromin mutants that exhibit allele specificity or increased Ras affinity resulting in suppression of activated ras alleles.

Morcos P et al.

Molecular and Cellular Biology, 1996

Differing structural requirements for GTPase-activating protein responsiveness and NADPH oxidase activation by Rac.

Xu X et al.

The Journal of Biological Chemistry, 1994

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."