Varaico: Literature-Extracted Genetic Variants

Gene:TRPM8
Variant:p.Y745H
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TRPM8

NM_024080.5:p.Y745H

Associated Papers

Molecular mechanisms underlying menthol binding and activation of TRPM8 ion channel.

Xu L et al.

Nature Communications, 2020

Evolutionary adaptation revealed by comparative genome analysis of woolly mammoths and elephants.

Smith SD et al.

Dna Research : an International Journal for Rapid Publication of Reports on Genes and Genomes, 2017

Implications of Human Transient Receptor Potential Melastatin 8 (TRPM8) Channel Gating from Menthol Binding Studies of the Sensing Domain.

Rath P et al.

Biochemistry, 2016

TRPM8 voltage sensor mutants reveal a mechanism for integrating thermal and chemical stimuli.

Voets T et al.

Nature Chemical Biology, 2007

High-throughput random mutagenesis screen reveals TRPM8 residues specifically required for activation by menthol.

Bandell M et al.

Nature Neuroscience, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."