Varaico: Literature-Extracted Genetic Variants

Gene:TRPV1
Variant:p.G563S
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TRPV1

NM_080704.4:p.G563S

Associated Papers

Cholesterol inhibits capsaicin activation of the TRPV1 channel.

Brandwine-Shemmer T et al.

Channels (austin, Tex.), 2026

The S4---S5 linker - gearbox of TRP channel gating.

Hofmann L et al.

Cell Calcium, 2017

Gain-of-function mutations in the transient receptor potential channels TRPV1 and TRPA1: how painful?

Boukalova S et al.

Physiological Research, 2014

Functionally important amino acid residues in the transient receptor potential vanilloid 1 (TRPV1) ion channel--an overview of the current mutational data.

Winter Z et al.

Molecular Pain, 2013

Protons stabilize the closed conformation of gain-of-function mutants of the TRPV1 channel.

Boukalova S et al.

Biochimica Et Biophysica Acta, 2013

Conserved residues within the putative S4-S5 region serve distinct functions among thermosensitive vanilloid transient receptor potential (TRPV) channels.

Boukalova S et al.

The Journal of Biological Chemistry, 2010

TRPV1 gain-of-function mutation impairs pain and itch sensations in mice.

Duo L et al.

Molecular Pain, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."