Associated Papers
Mapping variant effects on anti-tumor hallmarks of primary human T cells with base-editing screens.
Walsh ZH et al.
Nature Biotechnology, 2025
Massively parallel base editing screens to map variant effects on anti-tumor hallmarks of primary human T cells.
Walsh ZH et al.
Biorxiv : the Preprint Server for Biology, 2023
TSC2 S1365A mutation potently regulates CD8+ T cell function and differentiation and improves adoptive cellular cancer therapy.
Patel CH et al.
Jci Insight, 2023
Metabolic remodeling precedes mTORC1-mediated cardiac hypertrophy.
Davogustto GE et al.
Journal of Molecular and Cellular Cardiology, 2021
MTORC1-Regulated Metabolism Controlled by TSC2 Limits Cardiac Reperfusion Injury.
Oeing CU et al.
Circulation Research, 2021
PKG1α Cysteine-42 Redox State Controls mTORC1 Activation in Pathological Cardiac Hypertrophy.
Oeing CU et al.
Circulation Research, 2020
PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress.
Ranek MJ et al.
Nature, 2019
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