Varaico: Literature-Extracted Genetic Variants

Gene:TSC2
Variant:p.S1387A
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TSC2

NM_000548.5:p.S1387A

Associated Papers

MAP4K3 inhibits Sirtuin-1 to repress the LKB1-AMPK pathway to promote amino acid-dependent activation of the mTORC1 complex.

Branch MR et al.

Life Science Alliance, 2023

37221017 (PubMed )
Supplement: LSA-2022-01525_review_history.pdf

Dampened VEPH1 activates mTORC1 signaling by weakening the TSC1/TSC2 association in hepatocellular carcinoma.

Dong P et al.

Journal of Hepatology, 2020

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."