Varaico: Literature-Extracted Genetic Variants

Gene:TSC2
Variant:p.R1745P
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TSC2

NM_000548.5:p.R1745P

Associated Papers

Design of negative-regulating proteins of Rheb/mTORC1 with much-reduced sizes of the tuberous sclerosis protein complex.

Fu W et al.

Protein Science : a Publication of the Protein Society, 2023

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling.

Inoki K et al.

Nature Cell Biology, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."