Varaico: Literature-Extracted Genetic Variants

Gene:TSHR
Variant:p.E251K
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TSHR

NM_000369.5:p.E251K

Associated Papers

Novel information on the epitope of an inverse agonist monoclonal antibody provides insight into the structure of the TSH receptor.

Chen CR et al.

Plos One, 2012

The hinge region of human thyroid-stimulating hormone (TSH) receptor operates as a tunable switch between hormone binding and receptor activation.

Majumdar R et al.

Plos One, 2012

Thyrotropin (TSH) receptor residue E251 in the extracellular leucine-rich repeat domain is critical for linking TSH binding to receptor activation.

Chen CR et al.

Endocrinology, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."