Varaico: Literature-Extracted Genetic Variants

Gene:TSHR
Variant:p.S281G
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TSHR

NM_000369.5:p.S281G

Associated Papers

An aromatic environment in the vicinity of serine 281 is a structural requirement for thyrotropin receptor function.

Jaeschke H et al.

Endocrinology, 2006

Effects of mutations involving the highly conserved S281HCC motif in the extracellular domain of the thyrotropin (TSH) receptor on TSH binding and constitutive activity.

Ho SC et al.

Endocrinology, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."