Associated Papers
Genetic testing can change diagnosis and treatment in children with congenital hypothyroidism.
Kara C et al.
European Thyroid Journal, 2023
TSHR is the main causative locus in autosomal recessively inherited thyroid dysgenesis.
Cangul H et al.
Journal of Pediatric Endocrinology & Metabolism : Jpem, 2012
Interactions between the extracellular domain and the extracellular loops as well as the 6th transmembrane domain are necessary for TSH receptor activation.
Neumann S et al.
European Journal of Endocrinology, 2005
Aspartate-474 in the first exoplasmic loop of the thyrotropin receptor is crucial for receptor activation.
Kosugi S et al.
Febs Letters, 1997
Select a paper to view details