Varaico: Literature-Extracted Genetic Variants

Gene:TSHR
Variant:p.L587V
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TSHR

NM_000369.5:p.L587V

Associated Papers

Molecular sampling of the allosteric binding pocket of the TSH receptor provides discriminative pharmacophores for antagonist and agonists.

Hoyer I et al.

Biochemical Society Transactions, 2013

From molecular details of the interplay between transmembrane helices of the thyrotropin receptor to general aspects of signal transduction in family a G-protein-coupled receptors (GPCRs).

Kleinau G et al.

The Journal of Biological Chemistry, 2011

Signaling-sensitive amino acids surround the allosteric ligand binding site of the thyrotropin receptor.

Kleinau G et al.

Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."