Associated Papers
Profibrotic Biomarkers Correlate with Clinical Presentation and Outcome in Cardiac Transthyretin Amyloidosis.
Hein SJ et al.
International Journal of Molecular Sciences, 2025
Effectiveness and Utility of Genetic Testing in Establishing a Diagnosis of Hereditary Transthyretin Amyloidosis.
Singh A et al.
Journal of Clinical Medicine, 2025
Impact of mechanical stress on human transthyretin protein amyloid formation.
You M et al.
International Journal of Biological Macromolecules, 2025
Secretion of transthyretin: molecular mechanisms dependent on the endoplasmic reticulum.
Meng J et al.
Frontiers in Physiology, 2025
Prevalence, Cardiac Phenotype, and Outcomes of Transthyretin Variants in the UK Biobank Population.
Aung N et al.
Jama Cardiology, 2024
Transthyretin mutagenesis: impact on amyloidogenesis and disease.
Almeida ZL et al.
Critical Reviews in Clinical Laboratory Sciences, 2024
A natural history analysis of asymptomatic TTR gene carriers as they develop symptomatic transthyretin amyloidosis in the Transthyretin Amyloidosis Outcomes Survey (THAOS).
Coelho T et al.
Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis, 2022
Novel approaches to diagnosis and management of hereditary transthyretin amyloidosis.
Carroll A et al.
Journal of Neurology, Neurosurgery, and Psychiatry, 2022
Transthyretin cardiac amyloidosis in continental Western Europe: an insight through the Transthyretin Amyloidosis Outcomes Survey (THAOS).
Damy T et al.
European Heart Journal, 2022
[Diagnosis and treatment of cardiac transthyretin amyloidosis. Innovative therapy with tafamidis.]
Legrand D et al.
Revue Medicale De Liege, 2022
Hereditary transthyretin-related amyloidosis is frequent in polyneuropathy and cardiomyopathy of no obvious aetiology.
Skrahina V et al.
Annals of Medicine, 2021
Variant transthyretin amyloidosis (ATTRv) polyneuropathy in Greece: a broad overview with a focus on non-endemic unexplored regions of the country.
Koutsis G et al.
Neuromuscular Disorders : Nmd, 2021
Impaired in vitro growth response of plasma-treated cardiomyocytes predicts poor outcome in patients with transthyretin amyloidosis.
Hein S et al.
Clinical Research in Cardiology : Official Journal of the German Cardiac Society, 2021
Elevated interleukin-6 levels are associated with impaired outcome in cardiac transthyretin amyloidosis.
Hein SJ et al.
World Journal of Cardiology, 2021
TTRMDB: A database for structural and functional analysis on the impact of SNPs over transthyretin (TTR) using bioinformatic tools.
Srinivasan E et al.
Computational Biology and Chemistry, 2020
Quantitative sudomotor test helps differentiate transthyretin familial amyloid polyneuropathy from chronic inflammatory demyelinating polyneuropathy.
Fortanier E et al.
Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology, 2020
Magnetization transfer ratio quantifies polyneuropathy in hereditary transthyretin amyloidosis.
Kollmer J et al.
Annals of Clinical and Translational Neurology, 2020
Amyloidosis and Ocular Involvement: an Overview.
Dammacco R et al.
Seminars in Ophthalmology, 2020
Cryo-EM structure of a transthyretin-derived amyloid fibril from a patient with hereditary ATTR amyloidosis.
Schmidt M et al.
Nature Communications, 2019
A cell-based high-throughput screening method to directly examine transthyretin amyloid fibril formation at neutral pH.
Ueda M et al.
The Journal of Biological Chemistry, 2019
New sequence variants in patients affected by amyloidosis show transthyretin instability by isoelectric focusing.
Hinderhofer K et al.
Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis, 2019
Population diversity of the genetically determined TTR expression in human tissues and its implications in TTR amyloidosis.
Iorio A et al.
Bmc Genomics, 2017
Update on the clinical utility of an RNA interference-based treatment: focus on Patisiran.
Rizk M et al.
Pharmacogenomics and Personalized Medicine, 2017
Transthyretin Amyloidosis: A "Zebra" of Many Stripes.
Semigran MJ
Journal of the American College of Cardiology, 2016
Mechanism of Action and Clinical Application of Tafamidis in Hereditary Transthyretin Amyloidosis.
Coelho T et al.
Neurology and Therapy, 2016
Sixty years of transthyretin familial amyloid polyneuropathy (TTR-FAP) in Europe: where are we now? A European network approach to defining the epidemiology and management patterns for TTR-FAP.
Parman Y et al.
Current Opinion in Neurology, 2016
Clinical proteome informatics workbench detects pathogenic mutations in hereditary amyloidoses.
Dasari S et al.
Journal of Proteome Research, 2014
Disease profile and differential diagnosis of hereditary transthyretin-related amyloidosis with exclusively cardiac phenotype: an Italian perspective.
Rapezzi C et al.
European Heart Journal, 2013
Characterization and stability of transthyretin isoforms in cerebrospinal fluid examined by immunoprecipitation and high-resolution mass spectrometry of intact protein.
Poulsen K et al.
Methods (san Diego, Calif.), 2012
Familial amyloidotic polyneuropathy and transthyretin.
Nagasaka T
Sub-cellular Biochemistry, 2012
S-sulfonation of transthyretin is an important trigger step in the formation of transthyretin-related amyloid fibril.
Nakanishi T et al.
Biochimica Et Biophysica Acta, 2010
SELDI-TOF mass spectrometry evaluation of variant transthyretins for diagnosis and pathogenesis of familial amyloidotic polyneuropathy.
Ueda M et al.
Clinical Chemistry, 2009
Novel methods for detecting amyloidogenic proteins in transthyretin related amyloidosis.
Ando Y et al.
Frontiers in Bioscience : a Journal and Virtual Library, 2008
The molecular biology and clinical features of amyloid neuropathy.
Benson MD et al.
Muscle & Nerve, 2007
Transthyretin and familial amyloidotic polyneuropathy. Recent progress in understanding the molecular mechanism of neurodegeneration.
Hou X et al.
The Febs Journal, 2007
Transthyretin RNA profiling in livers from transplanted patients affected by familial amyloidotic polyneuropathy, and identification of a dual transcription start point.
Rimessi P et al.
Liver International : Official Journal of the International Association for the Study of the Liver, 2006
The hereditary amyloidoses.
Benson MD
Best Practice & Research. Clinical Rheumatology, 2003
X-ray absorption spectroscopy reveals a substantial increase of sulfur oxidation in transthyretin (TTR) upon fibrillization.
Gales L et al.
The Journal of Biological Chemistry, 2003
Transthyretin: a review from a structural perspective.
Hamilton JA et al.
Cellular and Molecular Life Sciences : Cmls, 2001
Transthyretin mutations in hyperthyroxinemia and amyloid diseases.
Saraiva MJ
Human Mutation, 2001
A comparative analysis of 23 structures of the amyloidogenic protein transthyretin.
Hörnberg A et al.
Journal of Molecular Biology, 2000
Electrically neutral microheterogeneity of human plasma transthyretin (prealbumin) detected by isoelectric focusing in urea gradients.
Altland K et al.
Electrophoresis, 1999