Varaico: Literature-Extracted Genetic Variants

Gene:TUBB
Variant:p.L228F
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TUBB

NM_178014.4:p.L228F

Associated Papers

Molecular simulations of paclitaxel binding to mutant β-tubulin: insights into chemotherapy resistance.

Vottero P et al.

Journal of Computer-aided Molecular Design, 2025

A beta-tubulin leucine cluster involved in microtubule assembly and paclitaxel resistance.

Gonzalez-Garay ML et al.

The Journal of Biological Chemistry, 1999

Overexpression of class I, II or IVb beta-tubulin isotypes in CHO cells is insufficient to confer resistance to paclitaxel.

Blade K et al.

Journal of Cell Science, 1999

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."