Varaico: Literature-Extracted Genetic Variants

Gene:TUBB
Variant:p.T274I
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TUBB

NM_178014.4:p.T274I

Associated Papers

Systematic in vitro evolution in Plasmodium falciparum reveals key determinants of drug resistance.

Luth MR et al.

Science (new York, N.y.), 2024

Identification of novel TUBB1 variants in patients with macrothrombocytopenia.

Çalışkaner ZO et al.

Turkish Journal of Medical Sciences, 2021

Structural insight into the mechanism of epothilone A bound to beta-tubulin and its mutants at Arg282Gln and Thr274Ile.

Shi G et al.

Journal of Biomolecular Structure & Dynamics, 2012

Wild-type class I beta-tubulin sensitizes Taxol-resistant breast adenocarcinoma cells harboring a beta-tubulin mutation.

Wiesen KM et al.

Cancer Letters, 2007

The roles of beta-tubulin mutations and isotype expression in acquired drug resistance.

Huzil JT et al.

Cancer Informatics, 2007

Do beta-tubulin mutations have a role in resistance to chemotherapy?

Berrieman HK et al.

The Lancet. Oncology, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."