Varaico: Literature-Extracted Genetic Variants

Gene:TUBB
Variant:p.R282Q
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TUBB

NM_178014.4:p.R282Q

Associated Papers

Mutations in the β-tubulin TUBB impair ciliogenesis and are associated with ciliopathy-like phenotypes.

Mollica A et al.

Nature Communications, 2025

41309602 (PubMed )
Supplement: 41467_2025_65634_MOESM1_ESM.pdf

Structural insight into the mechanism of epothilone A bound to beta-tubulin and its mutants at Arg282Gln and Thr274Ile.

Shi G et al.

Journal of Biomolecular Structure & Dynamics, 2012

Do beta-tubulin mutations have a role in resistance to chemotherapy?

Berrieman HK et al.

The Lancet. Oncology, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."