Varaico: Literature-Extracted Genetic Variants

Gene:TUBB
Variant:p.Y422C
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TUBB

NM_178014.4:p.Y422C

Associated Papers

Cancer cells acquire mitotic drug resistance properties through beta I-tubulin mutations and alterations in the expression of beta-tubulin isotypes.

Cheung CH et al.

Plos One, 2010

Wild-type class I beta-tubulin sensitizes Taxol-resistant breast adenocarcinoma cells harboring a beta-tubulin mutation.

Wiesen KM et al.

Cancer Letters, 2007

Do beta-tubulin mutations have a role in resistance to chemotherapy?

Berrieman HK et al.

The Lancet. Oncology, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."