Varaico: Literature-Extracted Genetic Variants

Gene:TXN
Variant:p.C32S
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TXN

NM_003329.4:p.C32S

Associated Papers

Study on a Mechanism of Improving MaAPX1 Protein Activity by Mutating Methionine to Lysine.

Xiao L et al.

Antioxidants (basel, Switzerland), 2024

Thioredoxin regulates the redox state and the activity of the human tRNA ligase complex.

Jaksch D et al.

Rna (new York, N.y.), 2023

Structural basis for thioredoxin-mediated suppression of NLRP1 inflammasome.

Zhang Z et al.

Nature, 2023

Structural and Biochemical Characterization of Thioredoxin-2 from Deinococcus radiodurans.

Kim MK et al.

Antioxidants (basel, Switzerland), 2021

34829714 (PubMed )
Supplement: antioxidants-10-01843-s001.zip › antioxidants-1464755-supplementary.pdf

Compensatory Protection of Thioredoxin-Deficient Cells from Etoposide-Induced Cell Death by Selenoprotein W via Interaction with 14-3-3.

Kang H et al.

International Journal of Molecular Sciences, 2021

An intracellular assay for activity screening and characterization of glutathione-dependent oxidoreductases.

Zimmermann J et al.

Free Radical Biology & Medicine, 2021

Free-energy landscapes of membrane co-translocational protein unfolding.

Rosen CB et al.

Communications Biology, 2020

ATM inhibition enhances Auranofin-induced oxidative stress and cell death in lung cell lines.

Ehrenfeld V et al.

Plos One, 2020

Plasmodium falciparum antioxidant protein reveals a novel mechanism for balancing turnover and inactivation of peroxiredoxins.

Staudacher V et al.

Free Radical Biology & Medicine, 2015

A redox-dependent mechanism for regulation of AMPK activation by Thioredoxin1 during energy starvation.

Shao D et al.

Cell Metabolism, 2014

Thioredoxin inhibits MPK38-induced ASK1, TGF-β, and p53 function in a phosphorylation-dependent manner.

Manoharan R et al.

Free Radical Biology & Medicine, 2013

Structural insights into the dehydroascorbate reductase activity of human omega-class glutathione transferases.

Zhou H et al.

Journal of Molecular Biology, 2012

Redox status of thioredoxin-1 (TRX1) determines the sensitivity of human liver carcinoma cells (HepG2) to arsenic trioxide-induced cell death.

Tian C et al.

Cell Research, 2008

Design of disulfide-linked thioredoxin dimers and multimers through analysis of crystal contacts.

Das M et al.

Journal of Molecular Biology, 2007

Redox-regulated cochaperone activity of the human DnaJ homolog Hdj2.

Choi HI et al.

Free Radical Biology & Medicine, 2006

Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: a mechanism for the functional loss of PTEN's tumor suppressor activity.

Meuillet EJ et al.

Archives of Biochemistry and Biophysics, 2004

Crystal structure of the catalytic domain of a human thioredoxin-like protein.

Jin J et al.

European Journal of Biochemistry, 2002

Effects of buried charged groups on cysteine thiol ionization and reactivity in Escherichia coli thioredoxin: structural and functional characterization of mutants of Asp 26 and Lys 57.

Dyson HJ et al.

Biochemistry, 1997

The Gly74-->Ser and Ser3-->Ala mutations in Rhodobacter sphaeroides Y thioredoxin: effects on active site reactivity and protein interaction.

Pille S et al.

European Journal of Biochemistry, 1996

Genetic analysis of the interaction between bacteriophage T7 DNA polymerase and Escherichia coli thioredoxin.

Himawan JS et al.

Proceedings of the National Academy of Sciences of the United States of America, 1992

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."