Varaico: Literature-Extracted Genetic Variants

Gene:TYK2
Variant:p.E957D
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TYK2

NM_003331.5:p.E957D

Associated Papers

Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma.

Prutsch N et al.

Leukemia, 2019

Germline activating TYK2 mutations in pediatric patients with two primary acute lymphoblastic leukemia occurrences.

Waanders E et al.

Leukemia, 2017

Tyrosine kinase 2 - Surveillant of tumours and bona fide oncogene.

Leitner NR et al.

Cytokine, 2017

Development of Selective Covalent Janus Kinase 3 Inhibitors.

Tan L et al.

Journal of Medicinal Chemistry, 2015

Kinome-wide selectivity profiling of ATP-competitive mammalian target of rapamycin (mTOR) inhibitors and characterization of their binding kinetics.

Liu Q et al.

The Journal of Biological Chemistry, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."