Varaico: Literature-Extracted Genetic Variants

Gene:TYK2
Variant:p.P216fs
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TYK2

NM_003331.5:p.P216fs

Associated Papers

A Novel Homozygous Mutation Causing Complete TYK2 Deficiency, with Severe Respiratory Viral Infections, EBV-Driven Lymphoma, and Jamestown Canyon Viral Encephalitis.

Roussel L et al.

Journal of Clinical Immunology, 2023

Impaired IL-23-dependent induction of IFN-γ underlies mycobacterial disease in patients with inherited TYK2 deficiency.

Ogishi M et al.

The Journal of Experimental Medicine, 2022

Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia.

Zhang Q et al.

The Journal of Experimental Medicine, 2022

A New Patient with Inherited TYK2 Deficiency.

Sarrafzadeh SA et al.

Journal of Clinical Immunology, 2020

Mycobacterium Intracellulare Infection Associated with TYK2 Deficiency: A Case Report and Review of the Literature.

Guo W et al.

Infection and Drug Resistance, 2020

Tyrosine kinase 2 is not limiting human antiviral type III interferon responses.

Fuchs S et al.

European Journal of Immunology, 2016

A new heterozygous TYK2 gene mutation: Case report and review of the literature.

Xie L et al.

International Journal of Immunopathology and Pharmacology, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."