Varaico: Literature-Extracted Genetic Variants

Gene:TYK2
Variant:p.S50fs
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TYK2

NM_003331.5:p.S50fs

Associated Papers

JAK/STAT in human diseases: a common axis in immunodeficiencies and hematological disorders.

Djidjik R et al.

Frontiers in Immunology, 2025

41438753 (PubMed )
Supplement: Table1.pdf

Impaired IL-23-dependent induction of IFN-γ underlies mycobacterial disease in patients with inherited TYK2 deficiency.

Ogishi M et al.

The Journal of Experimental Medicine, 2022

A New Patient with Inherited TYK2 Deficiency.

Sarrafzadeh SA et al.

Journal of Clinical Immunology, 2020

Tyrosine kinase 2 is not limiting human antiviral type III interferon responses.

Fuchs S et al.

European Journal of Immunology, 2016

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