Varaico: Literature-Extracted Genetic Variants

Gene:TYMS
Variant:p.A16V
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TYMS

NM_001071.4:p.A16V

Associated Papers

Combined spatial limitation around residues 16 and 108 of Plasmodium falciparum dihydrofolate reductase explains resistance to cycloguanil.

Vanichtanankul J et al.

Antimicrobial Agents and Chemotherapy, 2012

Novel Plasmodium vivax dhfr alleles from the Indonesian Archipelago and Papua New Guinea: association with pyrimethamine resistance determined by a Saccharomyces cerevisiae expression system.

Hastings MD et al.

Antimicrobial Agents and Chemotherapy, 2005

Mutational analysis of Plasmodium falciparum dihydrofolate reductase: the role of aspartate 54 and phenylalanine 223 on catalytic activity and antifolate binding.

Sirawaraporn W et al.

Molecular and Biochemical Parasitology, 2002

Antifolate drug resistance and point mutations in Plasmodium falciparum in Kenya.

Khan B et al.

Transactions of the Royal Society of Tropical Medicine and Hygiene, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."