Associated Papers
Molecular Mechanisms and Tumor Biological Aspects of 5-Fluorouracil Resistance in HCT116 Human Colorectal Cancer Cells.
Kurasaka C et al.
International Journal of Molecular Sciences, 2021
Computational study of the effects of protein tyrosine nitrations on the catalytic activity of human thymidylate synthase.
Jarmuła A et al.
Journal of Computer-aided Molecular Design, 2013
Design and characterization of a mutation outside the active site of human thymidylate synthase that affects ligand binding.
Cardinale D et al.
Protein Engineering, Design & Selection : Peds, 2010
Limits to thymidylate synthase and TP53 genes as predictive determinants for fluoropyrimidine sensitivity and further evidence for RNA-based toxicity as a major influence.
Brody JR et al.
Cancer Research, 2009
Elegance, silence and nonsense in the mutations literature for solid tumors.
Kern SE et al.
Cancer Biology & Therapy, 2006
Distribution of mutations in human thymidylate synthase yielding resistance to 5-fluorodeoxyuridine.
Kawate H et al.
The Journal of Biological Chemistry, 2002
Creation and characterization of 5-fluorodeoxyuridine-resistant Arg50 loop mutants of human thymidylate synthase.
Landis DM et al.
Cancer Research, 2001
Drug-resistant variants of Escherichia coli thymidylate synthase: effects of substitutions at Pro-254.
Fantz C et al.
Molecular Pharmacology, 2000
Protection of bone marrow cells from toxicity of chemotherapeutic agents targeted toward thymidylate synthase by transfer of mutant forms of human thymidylate synthase cDNA.
Banerjee D et al.
Progress in Experimental Tumor Research, 1999
Isolation and characterization of thymitaq (AG337) and 5-fluoro-2-deoxyuridylate-resistant mutants of human thymidylate synthase from ethyl methanesulfonate-exposed human sarcoma HT1080 cells.
Tong Y et al.
The Journal of Biological Chemistry, 1998
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