Associated Papers
Hotspots in an obligate homodimeric anticancer target. Structural and functional effects of interfacial mutations in human thymidylate synthase.
Salo-Ahen OM et al.
Journal of Medicinal Chemistry, 2015
Distribution of mutations in human thymidylate synthase yielding resistance to 5-fluorodeoxyuridine.
Kawate H et al.
The Journal of Biological Chemistry, 2002
Creation and characterization of 5-fluorodeoxyuridine-resistant Arg50 loop mutants of human thymidylate synthase.
Landis DM et al.
Cancer Research, 2001
Protection of bone marrow cells from toxicity of chemotherapeutic agents targeted toward thymidylate synthase by transfer of mutant forms of human thymidylate synthase cDNA.
Banerjee D et al.
Progress in Experimental Tumor Research, 1999
Isolation and characterization of thymitaq (AG337) and 5-fluoro-2-deoxyuridylate-resistant mutants of human thymidylate synthase from ethyl methanesulfonate-exposed human sarcoma HT1080 cells.
Tong Y et al.
The Journal of Biological Chemistry, 1998
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