Varaico: Literature-Extracted Genetic Variants

Gene:TYMS
Variant:p.D48E
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TYMS

NM_001071.4:p.D48E

Associated Papers

Hotspots in an obligate homodimeric anticancer target. Structural and functional effects of interfacial mutations in human thymidylate synthase.

Salo-Ahen OM et al.

Journal of Medicinal Chemistry, 2015

Creation and characterization of 5-fluorodeoxyuridine-resistant Arg50 loop mutants of human thymidylate synthase.

Landis DM et al.

Cancer Research, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."