Varaico: Literature-Extracted Genetic Variants

Gene:TYMS
Variant:p.D49G
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TYMS

NM_001071.4:p.D49G

Associated Papers

Distribution of mutations in human thymidylate synthase yielding resistance to 5-fluorodeoxyuridine.

Kawate H et al.

The Journal of Biological Chemistry, 2002

Creation and characterization of 5-fluorodeoxyuridine-resistant Arg50 loop mutants of human thymidylate synthase.

Landis DM et al.

Cancer Research, 2001

Drug-resistant variants of Escherichia coli thymidylate synthase: effects of substitutions at Pro-254.

Fantz C et al.

Molecular Pharmacology, 2000

Protection of bone marrow cells from toxicity of chemotherapeutic agents targeted toward thymidylate synthase by transfer of mutant forms of human thymidylate synthase cDNA.

Banerjee D et al.

Progress in Experimental Tumor Research, 1999

Isolation and characterization of thymitaq (AG337) and 5-fluoro-2-deoxyuridylate-resistant mutants of human thymidylate synthase from ethyl methanesulfonate-exposed human sarcoma HT1080 cells.

Tong Y et al.

The Journal of Biological Chemistry, 1998

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."