Associated Papers
Molecularly evolved thymidylate synthase inhibits 5-fluorodeoxyuridine toxicity in human hematopoietic cells.
Bielas JH et al.
Human Gene Therapy, 2009
Evolution toward small molecule inhibitor resistance affects native enzyme function and stability, generating acarbose-insensitive cyclodextrin glucanotransferase variants.
Kelly RM et al.
The Journal of Biological Chemistry, 2008
Distribution of mutations in human thymidylate synthase yielding resistance to 5-fluorodeoxyuridine.
Kawate H et al.
The Journal of Biological Chemistry, 2002
Creation and characterization of 5-fluorodeoxyuridine-resistant Arg50 loop mutants of human thymidylate synthase.
Landis DM et al.
Cancer Research, 2001
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