Varaico: Literature-Extracted Genetic Variants

Gene:U2AF2
Variant:p.N196K
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U2AF2

NM_007279.3:p.N196K

Associated Papers

Recurrent Neurodevelopmentally Associated Variants of the Pre-mRNA Splicing Factor U2AF2 Alter RNA Binding Affinities and Interactions.

Maji D et al.

Biochemistry, 2024

Early Splicing Complexes and Human Disease.

Nagasawa CK et al.

International Journal of Molecular Sciences, 2023

Monovalent Ionic Atmosphere Modulates the Selection of Suboptimal RNA Sequences by Splicing Factors' RNA Recognition Motifs.

Rozza R et al.

Journal of Chemical Information and Modeling, 2023

All-Atom Simulations Elucidate the Impact of U2AF2 Cancer-Associated Mutations on Pre-mRNA Recognition.

Rozza R et al.

Journal of Chemical Information and Modeling, 2022

Cytogenetic and Genetic Abnormalities with Diagnostic Value in Myelodysplastic Syndromes (MDS): Focus on the Pre-Messenger RNA Splicing Process.

Douet-Guilbert N et al.

Diagnostics (basel, Switzerland), 2022

Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal.

Glasser E et al.

Nucleic Acids Research, 2022

35524551 (PubMed )
Supplement: gkac287_Supplemental_Files.zip › gkac287Kielkopf_SupportingInformation_NAR-03120-A-2021.pdf

Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing.

Maji D et al.

The Journal of Biological Chemistry, 2020

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