Varaico: Literature-Extracted Genetic Variants

Gene:UBA52
Variant:p.K6R
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UBA52

NM_001033930.3:p.K6R

Associated Papers

A lineage-specific selective autophagy receptor module mediates P-body turnover.

Abdrakhmanov A et al.

Developmental Cell, 2026

Cullin-associated and neddylation-dissociated protein 1 (CAND1) promotes cardiomyocyte proliferation and heart regeneration by enhancing the ubiquitinated degradation of Mps one binder kinase activator 1b (Mob1b).

Li X et al.

Cell Death and Differentiation, 2025

Functional landscape of ubiquitin linkages couples K29-linked ubiquitylation to epigenome integrity.

Arroyo-Gomez J et al.

The Embo Journal, 2025

41125851 (PubMed )
Supplement: 44318_2025_599_MOESM13_ESM.zip › Figure_EV1.zip › Figure_EV1 › EV1G › EV1G.xlsx › Sheet1

Sugar-mediated non-canonical ubiquitination impairs Nrf1/NFE2L1 activation.

Yoshida Y et al.

Molecular Cell, 2024

SCFFBXW11 Complex Targets Interleukin-17 Receptor A for Ubiquitin-Proteasome-Mediated Degradation.

Jin B et al.

Biomedicines, 2024

K6-linked ubiquitylation marks formaldehyde-induced RNA-protein crosslinks for resolution.

Suryo Rahmanto A et al.

Molecular Cell, 2023

Regulation of STING activity in DNA sensing by ISG15 modification.

Lin C et al.

Cell Reports, 2023

Hyperubiquitylation of DNA helicase RECQL4 by E3 ligase MITOL prevents mitochondrial entry and potentiates mitophagy.

Hussain M et al.

The Journal of Biological Chemistry, 2023

37495109 (PubMed )
Supplement: mmc1.pdf

Orphan quality control shapes network dynamics and gene expression.

Mark KG et al.

Cell, 2023

Ring domains are essential for GATOR2-dependent mTORC1 activation.

Jiang C et al.

Molecular Cell, 2023

SPT16 ubiquitylation by DCAF14-CRL4 regulates FACT binding to histones.

Nakagawa T et al.

Cell Reports, 2022

DNA and RNA Cleavage Complexes and Repair Pathway for TOP3B RNA- and DNA-Protein Crosslinks.

Saha S et al.

Cell Reports, 2020

33378676 (PubMed )
Supplement: NIHMS1658640-supplement-1.pdf

Hepatitis B Core Protein Is Post-Translationally Modified through K29-Linked Ubiquitination.

Langerová H et al.

Cells, 2020

KEAP1 Mutations Drive Tumorigenesis by Suppressing SOX9 Ubiquitination and Degradation.

Shao N et al.

Advanced Science (weinheim, Baden-wurttemberg, Germany), 2020

33173725 (PubMed )
Supplement: ADVS-7-2001018-s001.pdf

Ubiquitination of DNA Damage-Stalled RNAPII Promotes Transcription-Coupled Repair.

Nakazawa Y et al.

Cell, 2020

Mutant TP53 posttranslational modifications: challenges and opportunities.

Nguyen TA et al.

Human Mutation, 2014

Assembly, analysis and architecture of atypical ubiquitin chains.

Hospenthal MK et al.

Nature Structural & Molecular Biology, 2013

23563141 (PubMed )
Supplement: NIHMS52102-supplement-1.pdf

Ascorbic acid conversion to erythroascorbic acid, mediated by ubiquitin.

Wang L et al.

Biochemical and Biophysical Research Communications, 2009

Regulating the p53 pathway: in vitro hypotheses, in vivo veritas.

Toledo F et al.

Nature Reviews. Cancer, 2006

Lys6-modified ubiquitin inhibits ubiquitin-dependent protein degradation.

Shang F et al.

The Journal of Biological Chemistry, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."