Varaico: Literature-Extracted Genetic Variants

Gene:UBA52
Variant:p.K33R
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UBA52

NM_001033930.3:p.K33R

Associated Papers

Cullin-associated and neddylation-dissociated protein 1 (CAND1) promotes cardiomyocyte proliferation and heart regeneration by enhancing the ubiquitinated degradation of Mps one binder kinase activator 1b (Mob1b).

Li X et al.

Cell Death and Differentiation, 2025

Functional landscape of ubiquitin linkages couples K29-linked ubiquitylation to epigenome integrity.

Arroyo-Gomez J et al.

The Embo Journal, 2025

Sugar-mediated non-canonical ubiquitination impairs Nrf1/NFE2L1 activation.

Yoshida Y et al.

Molecular Cell, 2024

Hyperubiquitylation of DNA helicase RECQL4 by E3 ligase MITOL prevents mitochondrial entry and potentiates mitophagy.

Hussain M et al.

The Journal of Biological Chemistry, 2023

37495109 (PubMed )
Supplement: mmc1.pdf

Orphan quality control shapes network dynamics and gene expression.

Mark KG et al.

Cell, 2023

K27-linked ubiquitylation promotes p97 substrate processing and is essential for cell proliferation.

Shearer RF et al.

The Embo Journal, 2022

SPT16 ubiquitylation by DCAF14-CRL4 regulates FACT binding to histones.

Nakagawa T et al.

Cell Reports, 2022

MITOL-dependent ubiquitylation negatively regulates the entry of PolγA into mitochondria.

Hussain M et al.

Plos Biology, 2021

33657094 (PubMed )
Supplement: pbio.3001139.s010.pdf

Rare CYLD Variants in Chinese Patients With Amyotrophic Lateral Sclerosis.

Gu X et al.

Frontiers in Genetics, 2021

DNA and RNA Cleavage Complexes and Repair Pathway for TOP3B RNA- and DNA-Protein Crosslinks.

Saha S et al.

Cell Reports, 2020

33378676 (PubMed )
Supplement: NIHMS1658640-supplement-1.pdf

Ubiquitination of DNA Damage-Stalled RNAPII Promotes Transcription-Coupled Repair.

Nakazawa Y et al.

Cell, 2020

BLM Potentiates c-Jun Degradation and Alters Its Function as an Oncogenic Transcription Factor.

Priyadarshini R et al.

Cell Reports, 2018

ASB2α, an E3 ubiquitin ligase specificity subunit, regulates cell spreading and triggers proteasomal degradation of filamins by targeting the filamin calponin homology 1 domain.

Razinia Z et al.

The Journal of Biological Chemistry, 2013

Proteasome beta-type subunits: unequal roles of propeptides in core particle maturation and a hierarchy of active site function.

Jäger S et al.

Journal of Molecular Biology, 1999

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."