Associated Papers
Two DOT1 enzymes cooperatively mediate efficient ubiquitin-independent histone H3 lysine 76 tri-methylation in kinetoplastids.
Frisbie VS et al.
Nature Communications, 2024
Cocrystallization of ubiquitin-deubiquitinase complexes through disulfide linkage.
Negron Teron KI et al.
Acta Crystallographica. Section D, Structural Biology, 2023
BARD1 reads H2A lysine 15 ubiquitination to direct homologous recombination.
Becker JR et al.
Nature, 2021
Structural insight into BRCA1-BARD1 complex recruitment to damaged chromatin.
Dai L et al.
Molecular Cell, 2021
Monoubiquitination of KRAS at Lysine104 and Lysine147 Modulates Its Dynamics and Interaction with Partner Proteins.
Nair VV et al.
The Journal of Physical Chemistry. B, 2021
Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction.
Grau D et al.
Nature Communications, 2021
Structural basis for the multi-activity factor Rad5 in replication stress tolerance.
Shen M et al.
Nature Communications, 2021
Cyanopyrrolidine Inhibitors of Ubiquitin Specific Protease 7 Mediate Desulfhydration of the Active-Site Cysteine.
Bashore C et al.
Acs Chemical Biology, 2020
PALB2 chromatin recruitment restores homologous recombination in BRCA1-deficient cells depleted of 53BP1.
Belotserkovskaya R et al.
Nature Communications, 2020
Structural Basis of H2B Ubiquitination-Dependent H3K4 Methylation by COMPASS.
Hsu PL et al.
Molecular Cell, 2019
Site-specific monoubiquitination activates Ras by impeding GTPase-activating protein function.
Baker R et al.
Nature Structural & Molecular Biology, 2013
Interactions between the three CIN85 SH3 domains and ubiquitin: implications for CIN85 ubiquitination.
Bezsonova I et al.
Biochemistry, 2008
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