Associated Papers
Convergence of orphan quality control pathways at a ubiquitin chain-elongating ligase.
Carrillo Roas S et al.
Molecular Cell, 2025
Endophilin-A Deficiency Induces the Foxo3a-Fbxo32 Network in the Brain and Causes Dysregulation of Autophagy and the Ubiquitin-Proteasome System.
Murdoch JD et al.
Cell Reports, 2016
Ubiquilins Chaperone and Triage Mitochondrial Membrane Proteins for Degradation.
Itakura E et al.
Molecular Cell, 2016
Intermediate filament aggregates cause mitochondrial dysmotility and increase energy demands in giant axonal neuropathy.
Israeli E et al.
Human Molecular Genetics, 2016
Phosphorylated ubiquitin chain is the genuine Parkin receptor.
Okatsu K et al.
The Journal of Cell Biology, 2015
The ubiquitin-proteasome system regulates the stability and activity of the glucose sensor glucokinase in pancreatic β-cells.
Hofmeister-Brix A et al.
The Biochemical Journal, 2013
Pathogen signatures activate a ubiquitination pathway that modulates the function of the metabolic checkpoint kinase mTOR.
Ivanov SS et al.
Nature Immunology, 2013
24121838 (PubMed )
Supplement: NIHMS520276-supplement-1.pdf
Monoubiquitination of EEA1 regulates endosome fusion and trafficking.
Ramanathan HN et al.
Cell & Bioscience, 2013
Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia.
Deng HX et al.
Nature, 2011
p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both.
Narendra D et al.
Autophagy, 2010
Lys6-modified ubiquitin inhibits ubiquitin-dependent protein degradation.
Shang F et al.
The Journal of Biological Chemistry, 2005
Direct binding of ubiquitin conjugates by the mammalian p97 adaptor complexes, p47 and Ufd1-Npl4.
Meyer HH et al.
The Embo Journal, 2002
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