Varaico: Literature-Extracted Genetic Variants

Gene:UBB
Variant:p.K6R
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UBB

NM_018955.4:p.K6R

Associated Papers

A lineage-specific selective autophagy receptor module mediates P-body turnover.

Abdrakhmanov A et al.

Developmental Cell, 2026

Cullin-associated and neddylation-dissociated protein 1 (CAND1) promotes cardiomyocyte proliferation and heart regeneration by enhancing the ubiquitinated degradation of Mps one binder kinase activator 1b (Mob1b).

Li X et al.

Cell Death and Differentiation, 2025

Functional landscape of ubiquitin linkages couples K29-linked ubiquitylation to epigenome integrity.

Arroyo-Gomez J et al.

The Embo Journal, 2025

41125851 (PubMed )
Supplement: 44318_2025_599_MOESM13_ESM.zip › Figure_EV1.zip › Figure_EV1 › EV1G › EV1G.xlsx › Sheet1

Sugar-mediated non-canonical ubiquitination impairs Nrf1/NFE2L1 activation.

Yoshida Y et al.

Molecular Cell, 2024

SCFFBXW11 Complex Targets Interleukin-17 Receptor A for Ubiquitin-Proteasome-Mediated Degradation.

Jin B et al.

Biomedicines, 2024

K6-linked ubiquitylation marks formaldehyde-induced RNA-protein crosslinks for resolution.

Suryo Rahmanto A et al.

Molecular Cell, 2023

Regulation of STING activity in DNA sensing by ISG15 modification.

Lin C et al.

Cell Reports, 2023

Hyperubiquitylation of DNA helicase RECQL4 by E3 ligase MITOL prevents mitochondrial entry and potentiates mitophagy.

Hussain M et al.

The Journal of Biological Chemistry, 2023

37495109 (PubMed )
Supplement: mmc1.pdf

Orphan quality control shapes network dynamics and gene expression.

Mark KG et al.

Cell, 2023

Ring domains are essential for GATOR2-dependent mTORC1 activation.

Jiang C et al.

Molecular Cell, 2023

HECTD3 regulates the tumourigenesis of glioblastoma by polyubiquitinating PARP1 and activating EGFR signalling pathway.

Zhang G et al.

British Journal of Cancer, 2022

SPT16 ubiquitylation by DCAF14-CRL4 regulates FACT binding to histones.

Nakagawa T et al.

Cell Reports, 2022

DNA and RNA Cleavage Complexes and Repair Pathway for TOP3B RNA- and DNA-Protein Crosslinks.

Saha S et al.

Cell Reports, 2020

Hepatitis B Core Protein Is Post-Translationally Modified through K29-Linked Ubiquitination.

Langerová H et al.

Cells, 2020

KEAP1 Mutations Drive Tumorigenesis by Suppressing SOX9 Ubiquitination and Degradation.

Shao N et al.

Advanced Science (weinheim, Baden-wurttemberg, Germany), 2020

33173725 (PubMed )
Supplement: ADVS-7-2001018-s001.pdf

Ubiquitination of DNA Damage-Stalled RNAPII Promotes Transcription-Coupled Repair.

Nakazawa Y et al.

Cell, 2020

Mutant TP53 posttranslational modifications: challenges and opportunities.

Nguyen TA et al.

Human Mutation, 2014

The TREX1 C-terminal region controls cellular localization through ubiquitination.

Orebaugh CD et al.

The Journal of Biological Chemistry, 2013

Molecular and structural insight into lysine selection on substrate and ubiquitin lysine 48 by the ubiquitin-conjugating enzyme Cdc34.

Suryadinata R et al.

Cell Cycle (georgetown, Tex.), 2013

Assembly, analysis and architecture of atypical ubiquitin chains.

Hospenthal MK et al.

Nature Structural & Molecular Biology, 2013

23563141 (PubMed )
Supplement: NIHMS52102-supplement-1.pdf

Regulating the p53 pathway: in vitro hypotheses, in vivo veritas.

Toledo F et al.

Nature Reviews. Cancer, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."