Varaico: Literature-Extracted Genetic Variants

Gene:UBB
Variant:p.K33R
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UBB

NM_018955.4:p.K33R

Associated Papers

Cullin-associated and neddylation-dissociated protein 1 (CAND1) promotes cardiomyocyte proliferation and heart regeneration by enhancing the ubiquitinated degradation of Mps one binder kinase activator 1b (Mob1b).

Li X et al.

Cell Death and Differentiation, 2025

Functional landscape of ubiquitin linkages couples K29-linked ubiquitylation to epigenome integrity.

Arroyo-Gomez J et al.

The Embo Journal, 2025

Sugar-mediated non-canonical ubiquitination impairs Nrf1/NFE2L1 activation.

Yoshida Y et al.

Molecular Cell, 2024

The TDRD3-USP9X complex and MIB1 regulate TOP3B homeostasis and prevent deleterious TOP3B cleavage complexes.

Saha S et al.

Nature Communications, 2023

Hyperubiquitylation of DNA helicase RECQL4 by E3 ligase MITOL prevents mitochondrial entry and potentiates mitophagy.

Hussain M et al.

The Journal of Biological Chemistry, 2023

37495109 (PubMed )
Supplement: mmc1.pdf

Orphan quality control shapes network dynamics and gene expression.

Mark KG et al.

Cell, 2023

HECTD3 regulates the tumourigenesis of glioblastoma by polyubiquitinating PARP1 and activating EGFR signalling pathway.

Zhang G et al.

British Journal of Cancer, 2022

SPT16 ubiquitylation by DCAF14-CRL4 regulates FACT binding to histones.

Nakagawa T et al.

Cell Reports, 2022

MITOL-dependent ubiquitylation negatively regulates the entry of PolγA into mitochondria.

Hussain M et al.

Plos Biology, 2021

33657094 (PubMed )
Supplement: pbio.3001139.s010.pdf

Differential Mutation Detection Capability Through Capture-Based Targeted Sequencing in Plasma Samples in Hepatocellular Carcinoma.

Gao J et al.

Frontiers in Oncology, 2021

33996539 (PubMed )
Supplement: DataSheet_8.xlsx › Table_S4

Rare CYLD Variants in Chinese Patients With Amyotrophic Lateral Sclerosis.

Gu X et al.

Frontiers in Genetics, 2021

DNA and RNA Cleavage Complexes and Repair Pathway for TOP3B RNA- and DNA-Protein Crosslinks.

Saha S et al.

Cell Reports, 2020

Ubiquitination of DNA Damage-Stalled RNAPII Promotes Transcription-Coupled Repair.

Nakazawa Y et al.

Cell, 2020

BLM Potentiates c-Jun Degradation and Alters Its Function as an Oncogenic Transcription Factor.

Priyadarshini R et al.

Cell Reports, 2018

ASB2α, an E3 ubiquitin ligase specificity subunit, regulates cell spreading and triggers proteasomal degradation of filamins by targeting the filamin calponin homology 1 domain.

Razinia Z et al.

The Journal of Biological Chemistry, 2013

Proteasome beta-type subunits: unequal roles of propeptides in core particle maturation and a hierarchy of active site function.

Jäger S et al.

Journal of Molecular Biology, 1999

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."