Associated Papers
The RBR E3 ubiquitin ligase HOIL-1 can ubiquitinate diverse non-protein substrates in vitro.
Wang XS et al.
Life Science Alliance, 2025
40169258 (PubMed )
Supplement: LSA-2025-03243_review_history.pdf
Convergence of orphan quality control pathways at a ubiquitin chain-elongating ligase.
Carrillo Roas S et al.
Molecular Cell, 2025
The HSPB1-p62/SQSTM1 functional complex regulates the unconventional secretion and transcellular spreading of the HD-associated mutant huntingtin protein.
Bonavita R et al.
Human Molecular Genetics, 2023
Ubiquilins Chaperone and Triage Mitochondrial Membrane Proteins for Degradation.
Itakura E et al.
Molecular Cell, 2016
27345149 (PubMed )
Supplement: mmc1.pdf
Intermediate filament aggregates cause mitochondrial dysmotility and increase energy demands in giant axonal neuropathy.
Israeli E et al.
Human Molecular Genetics, 2016
Genomic and Functional Analysis of the E3 Ligase PARK2 in Glioma.
Lin DC et al.
Cancer Research, 2015
Modeling non-hereditary mechanisms of Alzheimer disease during apoptosis in yeast.
Braun RJ et al.
Microbial Cell (graz, Austria), 2015
The ubiquitin-proteasome system regulates the stability and activity of the glucose sensor glucokinase in pancreatic β-cells.
Hofmeister-Brix A et al.
The Biochemical Journal, 2013
Pathogen signatures activate a ubiquitination pathway that modulates the function of the metabolic checkpoint kinase mTOR.
Ivanov SS et al.
Nature Immunology, 2013
24121838 (PubMed )
Supplement: NIHMS520276-supplement-1.pdf
The HECT domain of TRIP12 ubiquitinates substrates of the ubiquitin fusion degradation pathway.
Park Y et al.
The Journal of Biological Chemistry, 2009
Lys6-modified ubiquitin inhibits ubiquitin-dependent protein degradation.
Shang F et al.
The Journal of Biological Chemistry, 2005
Mutant ubiquitin found in neurodegenerative disorders is a ubiquitin fusion degradation substrate that blocks proteasomal degradation.
Lindsten K et al.
The Journal of Cell Biology, 2002
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