Associated Papers
APC/C-mediated ubiquitylation of extranucleosomal histone complexes lacking canonical degrons.
Skrajna A et al.
Nature Communications, 2025
Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C).
Bodrug T et al.
Nature Structural & Molecular Biology, 2023
Ubiquitin chain-elongating enzyme UBE2S activates the RING E3 ligase APC/C for substrate priming.
Martinez-Chacin RC et al.
Nature Structural & Molecular Biology, 2020
A quantitative analysis of cohesin decay in mitotic fidelity.
Carvalhal S et al.
The Journal of Cell Biology, 2018
An APC/C inhibitor stabilizes cyclin B1 by prematurely terminating ubiquitination.
Zeng X et al.
Nature Chemical Biology, 2012
K11-linked polyubiquitination in cell cycle control revealed by a K11 linkage-specific antibody.
Matsumoto ML et al.
Molecular Cell, 2010
Regulated degradation of spindle assembly factors by the anaphase-promoting complex.
Song L et al.
Molecular Cell, 2010
Identification of a physiological E2 module for the human anaphase-promoting complex.
Williamson A et al.
Proceedings of the National Academy of Sciences of the United States of America, 2009
Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex.
Jin L et al.
Cell, 2008
Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation.
Reddy SK et al.
Nature, 2007
Control of dTTP pool size by anaphase promoting complex/cyclosome is essential for the maintenance of genetic stability.
Ke PY et al.
Genes & Development, 2005
Autonomous regulation of the anaphase-promoting complex couples mitosis to S-phase entry.
Rape M et al.
Nature, 2004
Early mitotic degradation of the homeoprotein HOXC10 is potentially linked to cell cycle progression.
Gabellini D et al.
The Embo Journal, 2003
Structural and functional analysis of the human mitotic-specific ubiquitin-conjugating enzyme, UbcH10.
Lin Y et al.
The Journal of Biological Chemistry, 2002
Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN.
Stroschein SL et al.
Genes & Development, 2001
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