Varaico: Literature-Extracted Genetic Variants

Gene:UBE2G2
Variant:p.C89S
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UBE2G2

NM_003343.6:p.C89S

Associated Papers

A structurally conserved site in AUP1 binds the E2 enzyme UBE2G2 and is essential for ER-associated degradation.

Smith CE et al.

Plos Biology, 2021

STT3B-dependent posttranslational N-glycosylation as a surveillance system for secretory protein.

Sato T et al.

Molecular Cell, 2012

Autoregulation of an E2 enzyme by ubiquitin-chain assembly on its catalytic residue.

Ravid T et al.

Nature Cell Biology, 2007

The Hrd1p ligase complex forms a linchpin between ER-lumenal substrate selection and Cdc48p recruitment.

Gauss R et al.

The Embo Journal, 2006

A foldable CFTR{Delta}F508 biogenic intermediate accumulates upon inhibition of the Hsc70-CHIP E3 ubiquitin ligase.

Younger JM et al.

The Journal of Cell Biology, 2004

UPL1 and 2, two 405 kDa ubiquitin-protein ligases from Arabidopsis thaliana related to the HECT-domain protein family.

Bates PW et al.

The Plant Journal : for Cell and Molecular Biology, 1999

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."