Associated Papers
Complex Conformational Interplay for Parkin Activation is Revealed by 19F NMR Spectroscopy.
Connelly EM et al.
Journal of Molecular Biology, 2025
Additional feedforward mechanism of Parkin activation via binding of phospho-UBL and RING0 in trans.
Lenka DR et al.
Elife, 2024
Synergistic recruitment of UbcH7~Ub and phosphorylated Ubl domain triggers parkin activation.
Condos TE et al.
The Embo Journal, 2018
Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation.
Pao KC et al.
Nature Chemical Biology, 2016
Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Kumar A et al.
The Embo Journal, 2015
Catalytically Important Residues of E6AP Ubiquitin Ligase Identified Using Acid-Cleavable Photo-Cross-Linkers.
Krist DT et al.
Biochemistry, 2015
Biochemical and structural studies of a HECT-like ubiquitin ligase from Escherichia coli O157:H7.
Lin DY et al.
The Journal of Biological Chemistry, 2011
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