Varaico: Literature-Extracted Genetic Variants

Gene:UBE2L3
Variant:p.K48R
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UBE2L3

NM_003347.4:p.K48R

Associated Papers

The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs.

Yang S et al.

Molecular Cell, 2024

Mechanism of millisecond Lys48-linked poly-ubiquitin chain formation by cullin-RING ligases.

Liwocha J et al.

Nature Structural & Molecular Biology, 2024

PAICS ubiquitination recruits UBAP2 to trigger phase separation for purinosome assembly.

Chou MC et al.

Molecular Cell, 2023

Stepwise multipolyubiquitination of p53 by the E6AP-E6 ubiquitin ligase complex.

Masuda Y et al.

The Journal of Biological Chemistry, 2019

E6AP/UBE3A catalyzes encephalomyocarditis virus 3C protease polyubiquitylation and promotes its concentration reduction in virus-infected cells.

Carmody M et al.

Biochemical and Biophysical Research Communications, 2017

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."