Varaico: Literature-Extracted Genetic Variants

Gene:UGT1A1
Variant:p.L13_G14insFs
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UGT1A1

NM_000463.3:p.L13_G14insFs

Associated Papers

An evaluation of the performance of the PAP-PCR method in detecting UGT1A1 gene polymorphisms.

Kong X et al.

Molecular Biology Reports, 2025

A Case Report on Protease Serine 1 (PRSS1)-Related Acute Pancreatitis.

Vijayakumar V et al.

Cureus, 2025

Gilbert or Crigler-Najjar syndrome? Neonatal severe unconjugated hyperbilirubinemia with P364L UGT1A1 homozygosity.

Cozzi L et al.

Italian Journal of Pediatrics, 2022

[Study on spectrum of UGT1A1 mutations in connection with inherited non-hemolytic unconjugated hyperbilirubinemia].

Xiong QF et al.

Zhonghua Gan Zang Bing Za Zhi = Zhonghua Ganzangbing Zazhi = Chinese Journal of Hepatology, 2018

UGT1A1 genotypes and unconjugated hyperbilirubinemia phenotypes in post-neonatal Chinese children: A retrospective analysis and quantitative correlation.

Abuduxikuer K et al.

Medicine, 2018

Distribution of uridine diphosphate glucuronosyltransferase 1A polymorphisms and their role in irinotecan-induced toxicity in patients with cancer.

Wang Y et al.

Oncology Letters, 2017

Spectrum of UGT1A1 Variations in Chinese Patients with Crigler-Najjar Syndrome Type II.

Li L et al.

Plos One, 2015

Application of a combination of a knowledge-based algorithm and 2-stage screening to hypothesis-free genomic data on irinotecan-treated patients for identification of a candidate single nucleotide polymorphism related to an adverse effect.

Takahashi H et al.

Plos One, 2014

Pharmacogenetic study of deferasirox, an iron chelating agent.

Lee JW et al.

Plos One, 2013

Ethnic differences in the metabolism, toxicology and efficacy of three anticancer drugs.

Sai K et al.

Expert Opinion on Drug Metabolism & Toxicology, 2011

[Pharmacogenomics for adverse drug reactions].

Saito Y et al.

Nihon Rinsho. Japanese Journal of Clinical Medicine, 2010

Additive effects of drug transporter genetic polymorphisms on irinotecan pharmacokinetics/pharmacodynamics in Japanese cancer patients.

Sai K et al.

Cancer Chemotherapy and Pharmacology, 2010

UGT1A1*6 polymorphism is most predictive of severe neutropenia induced by irinotecan in Japanese cancer patients.

Onoue M et al.

International Journal of Clinical Oncology, 2009

Importance of UDP-glucuronosyltransferase 1A1*6 for irinotecan toxicities in Japanese cancer patients.

Sai K et al.

Cancer Letters, 2008

Irinotecan pharmacokinetics/pharmacodynamics and UGT1A genetic polymorphisms in Japanese: roles of UGT1A1*6 and *28.

Minami H et al.

Pharmacogenetics and Genomics, 2007

UGT1A1 haplotypes associated with reduced glucuronidation and increased serum bilirubin in irinotecan-administered Japanese patients with cancer.

Sai K et al.

Clinical Pharmacology and Therapeutics, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."