Associated Papers
Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform.
Kim B et al.
Translational and Clinical Pharmacology, 2021
Establishment of the experimental procedure for prediction of conjugation capacity in mutant UGT1A1.
Takaoka Y et al.
Plos One, 2019
Quantitative Atlas of Cytochrome P450, UDP-Glucuronosyltransferase, and Transporter Proteins in Jejunum of Morbidly Obese Subjects.
Miyauchi E et al.
Molecular Pharmaceutics, 2016
Performance of In Silico Tools for the Evaluation of UGT1A1 Missense Variants.
Rodrigues C et al.
Human Mutation, 2015
UGT1A1 genetic analysis as a diagnostic aid for individuals with unconjugated hyperbilirubinemia.
Skierka JM et al.
The Journal of Pediatrics, 2013
Gilbert and Crigler Najjar syndromes: an update of the UDP-glucuronosyltransferase 1A1 (UGT1A1) gene mutation database.
Canu G et al.
Blood Cells, Molecules & Diseases, 2013
Comprehensive analysis of UGT1A1 genetic polymorphisms in Chinese Tibetan and Han populations.
Zhang X et al.
Biochemical Genetics, 2012
Mutation Analysis in Crigler-Najjar Syndrome Type II-Case Report and Literature Review.
Ranjan P et al.
Journal of Clinical and Experimental Hepatology, 2011
Phenotype prediction of nonsynonymous single nucleotide polymorphisms in human phase II drug/xenobiotic metabolizing enzymes: perspectives on molecular evolution.
Hao D et al.
Science China. Life Sciences, 2010
Hyperbilirubinemia syndromes (Gilbert-Meulengracht, Crigler-Najjar, Dubin-Johnson, and Rotor syndrome).
Strassburg CP
Best Practice & Research. Clinical Gastroenterology, 2010
Natural history of Southeast Asian Ovalocytosis during the first 3 years of life.
Laosombat V et al.
Blood Cells, Molecules & Diseases, 2010
Exploring the genetic architecture of neonatal hyperbilirubinemia.
Watchko JF et al.
Seminars in Fetal & Neonatal Medicine, 2010
A molecular model of the human UDP-glucuronosyltransferase 1A1, its membrane orientation, and the interactions between different parts of the enzyme.
Laakkonen L et al.
Molecular Pharmacology, 2010
Gilbert-Meulengracht's syndrome and pharmacogenetics: is jaundice just the tip of the iceberg?
Strassburg CP
Drug Metabolism Reviews, 2010
Prediction of deleterious non-synonymous single-nucleotide polymorphisms of human uridine diphosphate glucuronosyltransferase genes.
Di YM et al.
The Aaps Journal, 2009
Family 1 uridine-5'-diphosphate glucuronosyltransferases (UGT1A): from Gilbert's syndrome to genetic organization and variability.
Strassburg CP et al.
Archives of Toxicology, 2008
Variability and function of family 1 uridine-5'-diphosphate glucuronosyltransferases (UGT1A).
Strassburg CP et al.
Critical Reviews in Clinical Laboratory Sciences, 2008
Influence of mutations associated with Gilbert and Crigler-Najjar type II syndromes on the glucuronidation kinetics of bilirubin and other UDP-glucuronosyltransferase 1A substrates.
Udomuksorn W et al.
Pharmacogenetics and Genomics, 2007
Adaptive evolution of multiple-variable exons and structural diversity of drug-metabolizing enzymes.
Li C et al.
Bmc Evolutionary Biology, 2007
Genetic variability, haplotypes, and htSNPs for exons 1 at the human UGT1A locus.
Thomas SS et al.
Human Mutation, 2006
Evaluation of mutation effects on UGT1A1 activity toward 17beta-estradiol using liquid chromatography-tandem mass spectrometry.
Wada K et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 2006
Frequencies of A(TA)7TAA, G71R, and G493R mutations of the UGT1A1 gene in the Malaysian population.
Yusoff S et al.
Biology of the Neonate, 2006
Racial variability in haplotype frequencies of UGT1A1 and glucuronidation activity of a novel single nucleotide polymorphism 686C> T (P229L) found in an African-American.
Kaniwa N et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2005
Transfection assays with allele-specific constructs: functional analysis of UDP-glucuronosyltransferase variants.
Jinno H et al.
Methods in Molecular Biology (clifton, N.j.), 2005
Comprehensive UGT1A1 genotyping in a Japanese population by pyrosequencing.
Saeki M et al.
Clinical Chemistry, 2003
[From gene to disease; unconjugated hyperbilirubinemia: Gilbert's syndrome and Crigler-Najjar types I and II].
Drenth JP et al.
Nederlands Tijdschrift Voor Geneeskunde, 2002
Novel missense mutation of the UGT1A1 gene in Thai siblings with Gilbert's syndrome.
Sutomo R et al.
Pediatrics International : Official Journal of the Japan Pediatric Society, 2002
Haplotype structures of the UGT1A gene complex in a Japanese population.
Saeki M et al.
The Pharmacogenomics Journal, 0
Hematologically important mutations: bilirubin UDP-glucuronosyltransferase gene mutations in Gilbert and Crigler-Najjar syndromes.
Costa E
Blood Cells, Molecules & Diseases, 0