Varaico: Literature-Extracted Genetic Variants

Gene:UGT1A1
Variant:p.T412T
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UGT1A1

NM_000463.3:p.T412T

Associated Papers

French-Speaking Network of Pharmacogenetics (RNPGx) Recommendations for Gene Panel Analysis Through Genotyping or Sequencing in Pharmacogenetics.

Picard N et al.

Fundamental & Clinical Pharmacology, 2026

Cardiovascular Pharmacogenomics: An Update on Clinical Studies of Antithrombotic Drugs in Brazilian Patients.

Hirata TDC et al.

Molecular Diagnosis & Therapy, 2021

Metabolic Effects of Aripiprazole and Olanzapine Multiple-Dose Treatment in a Randomised Crossover Clinical Trial in Healthy Volunteers: Association with Pharmacogenetics.

Koller D et al.

Advances in Therapy, 2021

33278020 (PubMed )
Supplement: 12325_2020_1566_MOESM1_ESM.docx

ABCB1 Genetic Variants as Predictors of Irinotecan-Induced Severe Gastrointestinal Toxicity in Metastatic Colorectal Cancer Patients.

Riera P et al.

Frontiers in Pharmacology, 2020

Relevance of Pharmacogenomics and Multidisciplinary Management in a Young-Elderly Patient With KRAS Mutant Colorectal Cancer Treated With First-Line Aflibercept-Containing Chemotherapy.

Bruera G et al.

Frontiers in Oncology, 2020

Intensive first-line FIr-C/FOx-C association of triplet chemotherapy plus cetuximab in RAS wild-type metastatic colorectal cancer patients: preliminary phase II data and prediction of individual limiting toxicity syndromes by pharmacogenomic biomarkers.

Bruera G et al.

Therapeutic Advances in Medical Oncology, 2019

ABCB1 polymorphism is associated with atorvastatin-induced liver injury in Japanese population.

Fukunaga K et al.

Bmc Genetics, 2016

Ethnic differences in the metabolism, toxicology and efficacy of three anticancer drugs.

Sai K et al.

Expert Opinion on Drug Metabolism & Toxicology, 2011

Pharmacogenomics: a tool for improving cancer chemotherapy.

Monzó M et al.

Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2008

[Role of pharmacogenetics in chemotherapy of colorectal cancers].

Ceppa F et al.

La Revue De Medecine Interne, 2007

Pharmacogenetically relevant polymorphisms in Portugal.

Oliveira E et al.

Pharmacogenomics, 2007

Pharmacogenomics of colorectal cancer prevention and treatment.

Nguyen H et al.

Cancer Investigation, 2006

Predicting drug response and toxicity based on gene polymorphisms.

Robert J et al.

Critical Reviews in Oncology/hematology, 2005

Pharmacogenetics of tipifarnib (R115777) transport and metabolism in cancer patients.

Sparreboom A et al.

Investigational New Drugs, 2004

Genetic predictors of the clinical response to opioid analgesics: clinical utility and future perspectives.

Lötsch J et al.

Clinical Pharmacokinetics, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."